BackgroundObtaining consent has become a standard way of respecting the patient’s rights and autonomy in clinical research. Ethical guidelines recommend that the child’s parent/s or authorised legal guardian provides informed consent for their child’s participation. However, obtaining informed consent in paediatric research is challenging. Parents become vulnerable because of stress related to their child’s illness. Understanding the views held by guardians and researchers about the consent process in Malawi, where there are limitations in health care access and research literacy will (...) assist in developing appropriate consent guidelines.MethodsWe conducted 20 in-depth interviews with guardians of children and research staff who had participated in paediatric clinical trial and observational studies in acute and non-acute settings in the Southern Region of Malawi. Interviews were audio-recorded, transcribed verbatim, and thematically analysed. Interviews were compared across studies and settings to identify differences and similarities in participants’ views about informed consent processes. Data analysis was facilitated by NVIVO 11 software.ResultsAll participants across study types and settings reported that they associated participating in research with therapeutic benefits. Substantial differences were noted in the decision-making process across study settings. Guardians from acute studies felt that the role of their spouses was neglected during consenting, while staff reported that they had problems obtaining consent from guardians when their partners were not present. Across all study types and settings, research staff reported that they emphasised the benefits more than the risks of the study to participants, due to pressure to recruit. Participants from non-acute settings were more likely to recall information shared during the consent process than participants in the acute setting.ConclusionThe health care context, culture and research process influenced participants’ understanding of study information across study types and settings. We advise research managers or principal investigators to define minimum requirements that would not compromise the consent process and conduct study specific training for staff. The use of one size fits all consent process may not be ideal. More guidance is needed on how these differences can be incorporated during the consent process to improve understanding and delivery of consent.Trial registration Not applicable. (shrink)

As COVID-19 spread, clinicians warned of mental illness epidemics within the coronavirus pandemic. Funding for digital mental health is surging and researchers are calling for widespread adoption to address the mental health sequalae of COVID-19. -/- We consider whether these technologies improve mental health outcomes and whether they exacerbate existing health inequalities laid bare by the pandemic. We argue the evidence for efficacy is weak and the likelihood of increasing inequalities is high. -/- First, we review recent trends in digital (...) mental health. Next, we turn to the clinical literature to show that many technologies proposed as a response to COVID-19 are unlikely to improve outcomes. Then, we argue that even evidence-based technologies run the risk of increasing health disparities. We conclude by suggesting that policymakers should not allocate limited resources to the development of many digital mental health tools and should focus instead on evidence-based solutions to address mental health inequalities. (shrink)

This article aims to formulate a philosophical problem that is grounded upon the Pan-Abrahamic nature of early Islam, focusing on the implications that this has for understanding the identity of the contemporary Islamic community. This philosophical problem—termed the Pan-Abrahamic Problem—is structured around the examination of Prophet Muhammad’s leadership and the inclusivity of the early Islamic community, as proposed by Fred Donner in the form of the Pan-Abrahamic Thesis. The formulation of this philosophical problem is presented through the lens of the (...) philosophical criteria of continuity and connectedness of aims (doctrine) and organisation, as proposed by Richard Swinburne. This philosophical problem will, thus, offer a challenge against traditional exclusivist narratives within Islam, ultimately aiming to emphasise the inclusive and pluralistic foundation of the religion and the significance of this for the contemporary Islamic identity. (shrink)

I show explicitly how concerns about wave function collapse and ontology can be decoupled from the bulk of technical analysis necessary to recover localized, approximately Newtonian trajectories from quantum theory. In doing so, I demonstrate that the account of classical behavior provided by decoherence theory can be straightforwardly tailored to give accounts of classical behavior on multiple interpretations of quantum theory, including the Everett, de Broglie-Bohm and GRW interpretations. I further show that this interpretation-neutral, decoherence-based account conforms to a general (...) view of inter-theoretic reduction in physics that I have elaborated elsewhere, which differs from the oversimplified and often ambiguous picture that treats reduction simply as a matter of taking limits. This interpretation-neutral account rests on a general three-pronged strategy for reduction between quantum and classical theories that combines decoherence, an appropriate form of Ehrenfest's Theorem, and a decoherence-compatible mechanism for collapse. It also incorporates a novel argument as to why branch-relative trajectories should be approximately Newtonian, which is based on a little-discussed extension of Ehrenfest's Theorem to open systems, rather than on the more commonly cited but less germane closed-systems version. In the Conclusion, I briefly suggest how the strategy for quantum-classical reduction described here might be extended to reduction between other classical and quantum theories, including classical and quantum field theory and classical and quantum gravity. (shrink)

Many of us are unmoved when it is objected that some morally or intellectually suspect source agrees with our belief. While we may tend to find this kind of guilt by epistemic association unproblematic, I argue that this tendency is a mistake. We sometimes face what I call the problem of unwelcome epistemic company. This is the problem of encountering agreement about the content of your belief from a source whose faults give you reason to worry about the belief's truth, (...) normative status, etiology, or implications. On the basis of an array of cases, I elaborate four distinct kinds of problems that unwelcome epistemic company poses. Two of these are distinctly epistemic, and two are moral. I canvass possible responses, ranging from stubbornness to an epistemic prudishness that avoids unwelcome company at all costs. Finally, I offer preliminary lessons of the problem and distinguish it from the problem of peer disagreement. (shrink)

Hubert Dreyfus argues that explicit thought disrupts smooth coping at both the level of everyday tasks and of highly-refined skills. However, Barbara Montero criticises Dreyfus for extending what she calls the ‘principle of automaticity’ from our everyday actions to those of trained experts. In this paper, I defend Dreyfus’ account while refining his phenomenology. I examine the phenomenology of what I call ‘esoteric’ expertise to argue that the explicit thought Montero invokes belongs rather to ‘gaps’ between or above moments of (...) reflexive coping. However, I agree that the ‘principle of automaticity’ does not adequately capture the experience of performing such skills. Drawing on examples of expert performance in sport and improvised music and dance, I argue that esoteric action, at its best, is marked by a distinct state of non-conceptual awareness- an experience of spontaneity, flow and ‘owned-ness’- that distinguishes it from the automaticity of everyday actions. (shrink)

In a previous volume of Ethical Theory & Moral Practice, Melis Erdur defends the provocative claim that postulating a stance-independent ground for morality constitutes a substantive moral mistake that is isomorphic to the substantive moral mistake that many realists attribute to antirealists. In this discussion paper I reconstruct Erdur’s argument and raise two objections to the general framework in which it arises. I close by explaining why rejecting Erdur’s approach doesn’t preclude normative criticism of metaethical theories.

In this article, I apply Australian logician and ecofeminist philosopher Val Plumwood’s Feminism and the Mastery of Nature, specifically its alternative logic of “the dance of interaction,” to a controversial community-engagement program in my home state of Alabama. At Rural Studio, Auburn University students design free housing and public works for one of the poorest regions in the United States, known as the “Black Belt.” Through the lens of Plumwood’s ecofeminist dancing logic, the marginalized source of Rural Studio’s survival is (...) revealed to be the resilience of the disempowered majority-Black community. Inspired thereby, I sketch an ecofeminist choreography with three “dancing” concepts (namely Plumwood’s “the master model,” Vandana Shiva’s “nature’s logic,” and Ariel Salleh’s “holding”), acknowledging the resilience of the disempowered as a necessary step toward an ethically-sustainable aesthetics. (shrink)

How do readers create representations of fictional worlds from texts? We hypothesize that readers use the real world as a starting point and investigate how much and which types of real-world information is imported into a given fictional world. We presented subjects with three stories and asked them to judge whether real world facts held true in the story world. Subjects' responses indicated that they imported many facts into fiction, though what exactly is imported depends on two main variables: the (...) distance that a narrative world lies from reality and the types of fact being imported. Facts that are true of the real world are more likely to be imported into worlds that are more similar to the real world, and facts that are more central to the representation of the real world are more likely to be imported overall. These results indicate that subjects make nuanced inferences when creating fictional worlds, basing their representations both on how different a story world is from the real world and on what they know to be causally central to the real world. (shrink)

This paper aims to uncover the explanatory profile of an idealized version of Karl Ernst von Baer’s notion of individuation, wherein the special develops from the general. First, because such sequences can only be exemplified by a multiplicity of causally-related events, they should be seen as the topics of historical why-questions, rather than initial condition why-questions. Second, because historical why-questions concern the diachronic unity or genidentity of the events under consideration, I argue that the von Baerian pattern elicits a distinctive (...) response to such questions, wherein we are inclined to simultaneously affirm and reject the temporal unity of these events. I buttress this claim by considering non-biological expressions of the von Baerian principle, drawn from institutional history and literature. In the second half of the paper, I consider the implications of my findings for ontogenetic and phylogenetic sequences. I argue that the explanatory profile of von Baer’s principle neatly describes the distinctive speciation events that characterize deep metazoan phylogeny, as described by Stuart Newman. I also argue that parallel considerations should move us to accept a sense in which ontogenetic stages are not diachronically unified. (shrink)

Today, liberals face a predicament: how to defend liberal principles, when adherence to them seems to constitute a fatal disadvantage against unprincipled opponents. The challenge is not new. In the early years of the twentieth century, liberalism was attacked, by critics on both the right and, especially, the left for being hypocritical, naïve, irresponsible, and impotent. It couldn't, for example (anti-liberalists thought), address the acute inequality of imperial rule, racial segregation, and socio-economic poverty. These issues of social justice it was (...) claimed by critics required a politics marked by an uncompromising commitment to ultimate ends, and an unrelenting use of power. Faced with such sentiments and the practical successes of anti-liberal ideologies (i.e. Fascism, Nazism, and Communism) liberals felt pressure to silence their scruples and doubts, and embrace the confidence, ruthlessness, and intransigence exhibited by their opponents. But doing so seemed tantamount to abandoning liberal hopes for, and commitments to, human freedom and all they valued in the first place. In Liberalism for Dark Times, Cherniss tells the story of the liberal response to this challenge in the twentieth century. Through a close study of five leading intellectuals engaged in these debates-Max Weber, Raymond Aron, Albert Camus, Reinhold Niebuhr, and Isaiah Berlin-Cherniss reconstructs a distinctive, neglected strand of liberal thought. This strand defines and defends liberalism as a political ethos: a complex of dispositions, temperament, and sensibility and style-which include skepticism; openness to experience; and careful, discriminating judgment-that shape how individuals make choices, meet challenges, understand and pursue possibilities, and conduct themselves toward others in the course of political struggle. In reconstructing the history of, what he calls, a tempered liberalism, and formulating it as a distinctive political perspective, Cherniss offers an alternative to the prevalent ways of thinking about both, liberalism's history and the intellectual resources available to it today. (shrink)

Do professional ethicists behave any morally better than other professors do? Do they show any greater consistency between their normative attitudes and their behavior? In response to a survey question, a large majority of professors (83 percent of ethicists, 83 percent of nonethicist philosophers, and 85 percent of nonphilosophers) expressed the view that “not consistently responding to student e-mails” is morally bad. A similarly large majority of professors claimed to respond to at least 95 percent of student e-mails. These professors, (...) and others, were sent three e-mails designed to look like queries from students. Ethicists’ e-mail response rates were not significantly different from the other two groups’. Expressed normative view correlated with self-estimated rate of e-mail responsiveness, especially among the ethicists. Empirically measured e-mail responsiveness, however, was at best weakly correlated with self-estimated e-mail responsiveness; and professors’ expressed normative attitude was not significantly correlated with empirically measured e-mail responsiveness for any of the three groups. (shrink)

Are properties perfectly natural (or not) relative to worlds, or are they perfectly natural (or not) tout court? That is, could there be a property P that is instanti-ated at worlds w1 and w2, and is perfectly natural at w1 but not at w2? Here, we offer an original argument for the non-world-relativity of perfect naturalness. Along the way, we reply to a prima facie compelling argument for the contin-gency of perfect naturalness, based upon the connection between natural prop-erties and (...) laws of nature. (shrink)

While developments of a shared intellectual tradition, the enactivist approach and the organizational account proffer importantly different accounts of organismic normativity. Where enactivists tend to follow Hans Jonas, Andres Weber, and Francisco Varela in grounding intrinsic affordance norms in existential concern, organizational theorists such as Alvaro Moreno, Matteo Mossio, and Leonardo Bich seek a more deflationary account of these normative phenomena. Critiques directed at both of these accounts of organismic normativity motivate the introduction of the precedential account of organismic normativity, (...) which I nevertheless locate within the enactivist approach, broadly construed. After detailing empirical evidence that would seem to vindicate the precedential account, I explore some of its implications. (shrink)

This paper is an investigation into the possibility of institutional agency and proceeds via the elaboration of two, nested claims. First, if genuine agency is attributable to certain social institutions, it would not be the full-blown, intentional agency that characterizes human activity, but would rather fall under a minimal modality of agency. Moreover, since enactivists aim to articulate minimal conceptions of agency that are applicable across the sphere of the living, this suggests that such accounts of minimal agency might additionally (...) be brought to bear onto some institutions. The second claim concerns which of two ideally typical enactivist accounts of minimal agency can more promisingly be applied to our institutions. Where some enactivists endorse a Jonasian account of minimal agency, which stresses a protentive, forward-looking orientation to a self-persistence goal, other enactivists apply a retentive ideal type of minimal agency, the norms of which are founded on a backward-looking responsiveness to precedent. By way of a critical analysis of structural functionalism, I argue that the retentive approach better explains the kind of agency that would be expressed by some institutions. I also claim that some philosophers, including Christian List, Philip Pettit and Ronald Dworkin, have independently come to the conclusion that institutional agency is retentive agency. (shrink)

Forgiveness has traditionally been characterized an affective response to a wrongdoing, i.e. a psychological process that involves ridding oneself of resentment or other negative reactive attitudes. In contrast to the prevailing model, this paper advocates for the emerging position that forgiveness should be understood as a normative power akin to a promise. In particular, I argue that forgiveness involves surrendering the right to discount the interests of a perpetrator (a special permission the victim acquires in virtue of having been wronged). (...) I argue that this model fits and/or explains important features of forgiveness, such as the idea that forgiveness is a personal response to a blameworthy wrong, that forgiveness re-establishes a relation of equality, and that forgiveness is ‘normatively significant’. I further develop the position by showing how it can provide a unified case of paradigmatic forgiveness, self-forgiveness, and third-party forgiveness—this explanatory power distinguishes the view from previous articulations of the idea that forgiveness is a normative power. The final section further explores these distinctions by delimiting the scope of forgiveness to exclude powers related to apologies, compensation, or ‘redemption’. (shrink)

This paper aims to extend in two directions the probabilistic dynamic epistemic logic provided in Kooi’s paper (J Logic Lang Inform 12(4):381–408, 2003) and to relate these extensions to ones made in van Benthem et al. (Proceedings of LOFT’06. Liverpool, 2006). Kooi’s probabilistic dynamic epistemic logic adds to probabilistic epistemic logic sentences that express consequences of public announcements. The paper (van Benthem et al., Proceedings of LOFT’06. Liverpool, 2006) extends (Kooi, J Logic Lang Inform 12(4):381–408, 2003) to using action models, (...) but in both papers, the probabilities are discrete, and are defined on trivial σ -algebras over finite sample spaces. The first extension offered in this paper is to add a previous-time operator to a probabilistic dynamic epistemic logic similar to Kooi’s in (J Logic Lang Inform 12(4):381–408, 2003). The other is to involve non-trivial σ -algebras and continuous probabilities in probabilistic dynamic epistemic logic. (shrink)

The paper studies in detail a precise formal construction of spacetime from matter suggested by the logician John Burgess. We presuppose a continuous and perdurantistic matter ontology. The result is a systematic method to translate claims about the geometry of a flat relativistic, or classical, spacetime into claims about geometrical relations between matter points. The approach is extended to electric and magnetic fields by treating them as multifields defined on matter, rather than as fields in the vacuum. A few tentative (...) suggestions are made to adapt the method to general relativity and to quantum theories. (shrink)

I defend three general claims concerning inter-theoretic reduction in physics. First, the popular notion that a superseded theory in physics is generally a simple limit of the theory that supersedes it paints an oversimplified picture of reductive relations in physics. Second, where reduction specifically between two dynamical systems models of a single system is concerned, reduction requires the existence of a particular sort of function from the state space of the low-level model to that of the high-level model that approximately (...) commutes, in a specific sense, with the rules of dynamical evolution prescribed by the models. The third point addresses a tension between, on the one hand, the frequent need to take into account system-specific details in providing a full derivation of the high-level theory’s success in a particular context, and, on the other hand, a desire to understand the general mechanisms and results that under- write reduction between two theories across a wide and disparate range of different systems; I suggest a reconciliation based on the use of partial proofs of reduction, designed to reveal these general mechanisms of reduction at work across a range of systems, while leaving certain gaps to be filled in on the basis of system-specific details. After discussing these points of general methodology, I go on to demonstrate their application to a number of particular inter-theory reductions in physics involving quantum theory. I consider three reductions: first, connecting classical mechanics and non-relativistic quantum mechanics; second,connecting classical electrodynamics and quantum electrodynamics; and third, connecting non-relativistic quantum mechanics and quantum electrodynamics. I approach these reductions from a realist perspective, and for this reason consider two realist interpretations of quantum theory - the Everett and Bohm theories - as potential bases for these reductions. Nevertheless, many of the technical results concerning these reductions pertain also more generally to the bare, uninterpreted formalism of quantum theory. Throughout my analysis, I make the application of the general methodological claims of the thesis explicit, so as to provide concrete illustration of their validity. (shrink)

Relationism is the view that our best physical theories can dispense with spacetime. To show the feasibility of relationism, philosophers have suggested a whole range of approaches, from the postulation of a physical plenum to the use of modality. Shamik Dasgupta has recently suggested using his Generalism to develop a relationist account of spacetime. This paper argues that Dasgupta’s Generalism offers no hope to the defenders of relationism. We first present Generalism in what we take to be its most perspicuous (...) formulation. We then discuss a recent argument by Sider (2020) against Generalism and show how to defuse it. Finally, we present a novel argument against Generalism based on Barrett’s criterion of parsimony (Barrett 2022). (shrink)

Dasgupta :35–67, 2009) has argued that material individuals, such as particles and laptops, are metaphysically objectionable and must be eliminated from our fundamental theories of the world. He proposes to eliminate them by redescribing all the fundamental facts of the world in a variant of predicate functor logic. We study the status, on this theory, of a putative fact particularly recalcitrant to a formulation within predicate functor logic: his own claim that there are no fundamental or primitive material individuals. We (...) consider three regimentations of the denial of primitive individuals and show that—under some plausible hypotheses about fundamental truths and the fundamentality operator—they cannot be consistently translated in predicate functor logic by Dasgupta’s usual strategy. We conclude by discussing two approaches to salvage Generalism, in the absence of such a translation. (shrink)

We argue that there exists a necessary causally potent being. We then argue that that being is God.

This chapter aims to develop an argument in support of the basic mentality thesis. A “counting” argument is constructed in the chapter that poses a problem for the identity thesis. Then, the chapter extends the “counting” argument in a way that exposes a problem for the dependence (mind grounded in physical) thesis. The basic strategy of a counting argument is to show that there is a greater quantity of members of the one category than of some other. To illustrate, the (...) chapter considers the categories integers and reals. These categories both have infinitely many members. To further illustrate the categorical difference between the physical and nonphysical, it also considers building a Lego tower. The divide between physical and nonphysical properties involves much more than a mere difference with respect to complexity of psychological content. Next, the chapter justifies the basic mentality thesis by considering the main arguments for standard physicalism (reductive or nonreductive). (shrink)

We develop and knit together several theodicies in order to find a more complete picture of why certain forms of animal suffering might be permitted by a perfect being. We focus on an especially potent form of the problem of evil, which arises from considering why a perfectly good, wise, and powerful God might use evolutionary mechanisms that predictably result in so much animal suffering and loss of life. There are many existing theodicies on the market, and although they offer (...) helpful resources, we combine and further develop several proposals to produce a composite theodicy that avoids certain shortcomings of the individual theodicies. An important element of our project is locating a role for randomness in cosmic and biological evolution. In particular, we show how randomness might enhance or enable certain goods, including everlasting goods, at the risk of temporary evils. (shrink)

Many of our spoken languages are endangered and rapidly becoming extinct. Due to this, there are attempts to preserve as many of those languages as possible. One preservation approach is combining data collection and artificial intelligence‐based language models. However, current data collection methods may only capture static data from a dynamic cognitive process. If data are not genuinely capturing the dynamic process, it raises questions about whether they capture all the essential knowledge about how a language functions. Here, we discuss (...) the implications of this issue and its importance in preserving endangered languages. (shrink)

This article examines some of the story conventions of network television news to explain the ways in which healthcare interest groups develop and maintain their presence in this medium—a process that has significant implications for public understanding of healthcare issues, and therefore to bioethics. The article is divided into three sections. The first section focuses on three major normative conventions of television news: adherence to a simple narrative structure, the balance ethic, and avoidance of the “think-piece” and outlines the basic (...) strategies available to interest groups for exploiting these normative conventions. Section two introduces three case studies of organizations and individuals who have run high-profile media campaigns. Section three explores the implications for bioethics of the observations made in this article. (shrink)

The earliest formulation of the Higgs naturalness argument has been criticized on the grounds that it relies on a particular cutoff-based regularization scheme. One response to this criticism has been to circumvent the worry by reformulating the naturalness argument in terms of a renormalized, regulator-independent parametrization. An alternative response is to deny that regulator dependence poses a problem for the naturalness argument, because nature itself furnishes a particular, physically correct regulator for any effective field theory in the form of that (...) EFT’s physical cutoff, together with an associated set of bare parameters that constitute the unique physically preferred “fundamental parameters” of the EFT. Here, I argue that both lines of defense against the initial worry about regulator dependence are flawed. I argue that reformulation of the naturalness argument in terms of renormalized parameters simply trades dependence on a particular regularization scheme for dependence on a particular renormalization scheme, and that one or another form of scheme dependence afflicts all formulations of the Higgs naturalness argument. Concerning the second response, I argue that the grounds for suspending the principle of regularization or renormalization scheme independence in favor of a physically preferred parametrization are thin; the assumption of a physically preferred parametrization, whether in the form of bare “fundamental parameters” or renormalized “physical parameters,” constitutes a theoretical idle wheel in generating the confirmed predictions of established EFTs, which are invariably scheme-independent. I highlight certain features of the alternative understanding of EFTs, and the EFT-based approach to understanding the foundations of QFT, that emerges when one abandons the assumption of a physically preferred parametrization. I explain how this understanding departs from several dogmas concerning the mathematical formulation and physical interpretation of EFTs in high-energy physics. (shrink)

I introduce new details in an argument for necessarily existing propositions. The crux of the argument marks out a pathway to the conclusion that necessary truths cannot themselves be necessarily true unless they necessarily exist. I motivate the steps in the argument and then address several standard objections, including one that makes use of the distinction between ‘truth in’ and ‘truth at’. The purpose of the argument is to generate deeper insights into the nature of propositions and the logic of (...) necessity. The argument also gives us a new reason to believe the traditional answer to the question of why there is anything: there is something because the alternative is impossible. (shrink)

According to socio-relational theory, men and women encountered different ecologies in their evolutionary past, and, as a result of different ancestral selection pressures, they developed different patterns of emotional expressivity that have persisted across cultures and large human evolutionary time scales. We question these assumptions, and propose that social-cognitive models of individual differences more parsimoniously account for sex differences in emotional expressivity.

Moral realism and some of its constitutive theses, e.g., cognitivism, face the following challenge. If they are true, then it seems that we should predict that deference to moral testimony is appropriate under the same conditions as deference to non-moral testimony. Yet, many philosophers intuit that deference to moral testimony is not appropriate, even in otherwise ordinary conditions. In this paper I show that the challenge is cogent only if the appropriateness in question is disambiguated in a particular way. To (...) count against realism and its constitutive theses, moral deference must fail to be appropriate in specifically the way that the theses predict it is appropriate. I argue that this is not the case. In brief, I argue that realism and allied theses predict only that deference to moral testimony is epistemically appropriate, but that the intuitive data plausibly show only that it is not morally appropriate. If I am right, then there is reason to doubt the metaethical relevance of much of the skepticism regarding moral deference in recent literature. (shrink)

ABSTRACTNew methods of calculating indices from the dot-probe task measure temporal dynamics in attention bias or fluctuations in attention bias towards and away from emotional stimuli over time. H...

Intuitively, vagueness involves some sort of indeterminacy: if Plato is a borderline case of baldness, then there is no fact of the matter about whether or not he’s bald—he’s neither bald nor not bald. The leading formal treatments of such indeterminacy—three valued logic, supervaluationism, etc.—either fail to validate the classical theorems, or require that various classically valid inference rules be restricted. Here we show how a fully classical, yet indeterminist account of vagueness can be given within natural semantics, an alternative (...) semantics for classical proof theory. The key features of the account are: there is a single notion of truth—definite truth—and a single notion of validity; sentences can be true, false, or undetermined; all classical theorems and all classical inference rule are valid; the sorites argument is unsound; ‘definitely’ is treated as a meta-language predicate; higher-order vagueness is handled via semantic ascent. (shrink)

I argue that ordinary confabulation is a side-effect of an interpretive faculty that makes sense of the world by rationalising our experience within the context of a personal and cultural narrative. However, I argue that a hyperactivity of the same process manifests as schizotypy—latent schizophrenic tendencies—that can lead to extreme dissociation of interpretation from experience. I first give a phenomenological account of the process of interpretation, arguing that it is enacted through the creation of conceptual cognitive content from an originary (...) non-conceptual experience. I then ground this account in empirical evidence, showing how our direct perception is moulded and adapted as it is conceptualised to fit our individual and collective expectations. Finally, I argue that hyperactive over-interpretation results in schizotypic dissociation, thus suggesting that schizophrenia should be understood as a disorder of interpretation, the extreme end of a spectrum that includes ordinary confabulation. (shrink)

Quine, taking the molecular constitution of matter as a paradigmatic example, offers an account of the relation between theory confirmation and ontology. Elsewhere, he deploys a similar ontological methodology to argue for the existence of mathematical objects. Penelope Maddy considers the atomic/molecular theory in more historical detail. She argues that the actual ontological practices of science display a positivistic demand for “direct observation,” and that fulfillment of this demand allows us to distinguish molecules and other physical objects from mathematical abstracta. (...) However, the confirmation of the atomic/molecular theory and the development of scientists’ ontological attitudes towards atoms was more complicated and subtle than even Maddy supposes. The present paper argues that the history of the theory in fact supports neither Quine’s and Maddy’s accounts of scientific ontology. There was no general demand from scientists to “see” atoms before they were reckoned to be real; but neither did the indispensable appearance of atoms in the best theory of chemical combination suffice to convince scientists of their reality. (shrink)

Fluorescence microscopy is the primary tool for studying complex processes inside individual living cells. Technical advances in both molecular biology and microscopy have made it possible to image cells from many genetic and environmental backgrounds. These images contain a vast amount of information, which is often hidden behind various sources of noise, convoluted with other information and stochastic in nature. Accessing the desired biological information therefore requires new tools of computational image analysis and modeling. Here, we review some of the (...) recent advances in computational analysis of images obtained from fluorescence microscopy, focusing on bacterial systems. We emphasize techniques that are readily available to molecular and cell biologists but also point out examples where problem‐specific image analyses are necessary. Thus, image analysis is not only a toolkit to be applied to new images but also an integral part of the design and implementation of a microscopy experiment. (shrink)

In order to account for how children can generalize words beyond a very limited set of labeled examples, Bloom's proposal of word learning requires two extensions: a better understanding of the “general learning and memory abilities” involved, and a principled framework for integrating multiple conflicting constraints on word meaning. We propose a framework based on Bayesian statistical inference that meets both of those needs.

Within the context of the so-called psychedelic renaissance, ketamine (C13H16CINO) has been increasingly used for therapeutic purposes. While ketamine clearly has healing powers, what interests me here is less ketamine for healing than what I will call the possibility of knowledge by ketamine. Drawing upon Deleuze and Guattari's arguments for the centrality of metal and metallurgy as a perspective on matter, I speculate that knowledge by ketamine is not identical with, yet verges on, a kind of becoming-metal of consciousness, and (...) an intuition of what Deleuze and Guattari call a ‘nonorganic life’ proper to matter. Ketamine trips provide vantage, and in some sense experience of that metallic dimension Deleuze and Guattari claim is inherent in all matter, a fluidity and transformability which for them is the basis of a hydraulic as opposed to solid model of matter, and clue to a vitality that supersedes the distinction of life and death. Intuition of the fundamentally hydraulic or metallic nature of matter is essential to what Deleuze and Guattari call a nomadic or ‘minor’ science, one that, because it centres continuous variation rather than discrete form, is capable of challenging the conservative tendencies of ‘major’ or State science. Without making claims for ketamine as in any sense sufficient for a becoming-metal of consciousness, ketamine may be constructively conjugated with other knowledges – knowledge by meditation, by dance, by music, or by martial arts, to name only a few. Such minor sciences of transformation and transmutation remain capable of a negative or corrosive relation to the State, despite the ever-present reality of recapture. (shrink)

It is often assumed that the first stage of many classical arguments for theism depends upon some version of the Principle of Sufficient Reason being true. Unfortunately for classical theists, PSR is a controversial thesis that has come under rather severe criticism in the contemporary literature. In this article, I grant for the sake of argument that every version of PSR is false. Thus, I concede with the critics of PSR, that it is possible that there is, at least, one (...) fact that is ontologically brute. I then proffer an epistemological challenge to ontological bruteness. Specifically, I argue that whenever a knowledge seeker, S, perceives some unexplained fact, F, it is never reasonable for S to believe F is ontologically brute. I conclude that, even if PSR is false, it is more reasonable to believe that the key premise in the first stage of classical arguments for theism is true. (shrink)

In Bernard Suits’ The Grasshopper and Return of the Grasshopper, game-play is claimed to be the ‘ideal of existence’ and the only activity that could sustain us through the ‘endless and endlessly boring summer’ of utopia. Christopher Yorke has challenged these claims by way of a constructive dilemma. If these games are sufficiently akin to the games we play, then they are not adequate to the task of rendering immortality tolerable. If these games are importantly different than the games we (...) play, then, in being ‘unknown and unknowable’, they would characterize a form of life that is importantly different from our own and, so, would be inappropriate objects of social and political aspiration. Against Yorke’s skepticism, I argue that the games that constitute the ideal of existence are intelligible to us because we already play what the Grasshopper calls ‘open games’. Steffen Borge concedes that utopian games are intelligible, but argues that such games would fail to ‘grab our minds and imagination’. In the second half of the paper, I contend, against Borge, that such open games are adequate to the task of sustaining the interest of an immortal community. (shrink)

I bring to light a set-theoretic reason to think that there are more mental properties than shapes, sizes, masses, and other characteristically “physical” properties. I make use of a couple counting principles. One principle, backed by a Cantorian-style argument, is that pluralities outnumber particulars: that is, there is a distinct plurality of particulars for each particular, but not vice versa. The other is a principle by which we may coherently identify distinct mental properties in terms of arbitrary pluralities of physical (...) properties. I motivate these principles and explain how they together imply that there are more mental properties than physical properties. I then argue that certain parody arguments fail for various instructive reasons. The purpose of my argument is to identify an unforeseen “counting” cost of a certain reductive materialist view of the mind. (shrink)

The target article argues researchers should be more ambitious, designing studies that systematically and comprehensively explore the space of possible experiments in one fell swoop. We argue that while “systematic” is rarely achievable, “comprehensive” is often enough. Critically, the recent popularization of massive online experiments shows that comprehensive studies are achievable for most cognitive and behavioral research questions.

This article examines the confessional booth as an architected space that, by serving as a geo-epistemological enclosure, prefigures digital forms of data capture and production. In conversation with critical scholarship about ‘confessional culture,’ it analyzes how confessionals and digital enclosures embody different historical iterations of a cultural technique that promises absolution – understood as a cleansing process of transparent exposure. It argues that, with digital enclosures, the renunciative self-mortification that lies at the heart of classic Christian confession is reprogrammed into (...) what Byung-Chul Han calls a ‘pornographic self-presentation.’ The self-death dealt by the confessional thus becomes an apparently voluntary self-exploitation for the social media subject. In both cases, however, absolution governs via rituals of cathartic transparency, submitting interiority to processes of legible exteriorization and articulating the subject via an exhibitive logic that blurs the boundaries between communicative freedom and compulsory self-exposure. (shrink)

In this essay I critique the identification of contingency with sheer arbitrary possibility in Quentin Meillassoux's After Finitude: An Essay on the Necessity of Contingency. After offering logical and metaphysical reasons for why such an identification is a limitation on the speculative potential of reason, I draw upon Charles S. Peirce, Gilles Deleuze, and Giambattista Vico to articulate the outlines of a view of contingency which can underwrite a different speculative position to one that is grounded upon an absolute of (...) unreason. This form of speculation, a realism of contingency without an axiom of unreason, is indicated in outline by the structure of divination practices. I thus propose, without defending its actuality, at least the possibility of a divinatory form of speculation that is adequate to the absolute status of contingency. (shrink)